Understand and engineer biomolecular machines

生体分子機械に学び、生体分子機械を創る

Welcome to IINO G at IMS 日本語

Protein molecular machines supporting life are far superior to synthetic molecular machines in many aspects [1, 2]. We unveil operation principles of protein molecular machines with single-molecule imaging and X-ray crystallography. With the help of saturation mutagenesis, automated screening and computational design, we also engineer non-natural protein molecular machines to understand their design principles.

See Research page for detail.

[1] The Nobel Prize in Chemistry 2016 "The design and synthesis of molecular machines"
[2] Peplow M. Nature 2015 "The tiniest Lego: a tale of nanoscale motors, rotors, switches and pumps"

 

Join our group 日本語

We welcome highly-motivated PhD students.

Contact: iino_at_ims.ac.jp (change _at_ to @)

News from our group, Old news