Understand and engineer biomolecular machines


Welcome to IINO G at IMS 日本語

Protein molecular machines supporting life are far superior to synthetic molecular machines in many aspects [1, 2]. We unveil operation principles of protein molecular machines with single-molecule imaging and X-ray crystallography. With the help of saturation mutagenesis, automated screening and computational design, we also engineer non-natural protein molecular machines to understand their design principles.

See Research page for detail.

[1] The Nobel Prize in Chemistry 2016 "The design and synthesis of molecular machines"
[2] Peplow M. Nature 2015 "The tiniest Lego: a tale of nanoscale motors, rotors, switches and pumps"


Join our group 日本語

We welcome highly-motivated PhD students.

Contact: iino_at_ims.ac.jp (change _at_ to @)

News from our group, Old news

[Recent Publications]

Mar 16, 2019 Umakoshi-san/Fukuda-san's paper has been published online in BBA Gereral Subjects! Collaboration with Prof. Uchihashi and Prof. Ando.
High-speed near-field fluorescence microscopy combined with high-speed atomic force microscopy for biological studies

[Presentations and Events]

July 25-27, 2019 Iino give a talk at Seoul Single-molecule Meeting@Seoul

Jun 3-7, 2019 Iino visit Princeton University, NJ, USA

May 30, 2019 Iino give a talk at Joint Meeting for Young Researchers -Frontiers in Imaging Probes and Technologies-@Okazaki

Mar 13, 2019 Iino give a talk at 24th Flagella Meeting @Gamagori, Japan

Mar 2-6, 2019 Iino give a presentation at Biophysical Society 63rd Annual Meeting @Baltimore, USA

Feb 11, 2019 Iino give a talk at NCCR Molecular Systems Engineering, University of Basel, Switzerland

Jan 21-24, 2019 Iino visit Princeton University, NJ, USA

Jan 15, 2019 Iino give a talk at LaSIE Seminar, Osaka University, Osaka, Japan