Understand and engineer biomolecular motors


Welcome to IINO G at IMS 日本語

Protein molecular motors supporting life are far superior to synthetic molecular machines in many aspects [1, 2]. We unveil operation principles of protein molecular motors with single-molecule imaging and X-ray crystallography. To understand their design principles, we also engineer non-natural protein molecular motors with saturation mutagenesis and automated screening.

See Research page for detail.

[1] The Nobel Prize in Chemistry 2016 "The design and synthesis of molecular machines"
[2] Peplow M. Nature 2015 "The tiniest Lego: a tale of nanoscale motors, rotors, switches and pumps"


Join our group 日本語

Assistant Professor position is available. Recruitment Details

Postdoctoral Research Fellow position is available. Joint research project with Prof. Haw Yang (Princeton). Mainly stay in Princeton to conduct research. Recruitment Details

We also welcome highly-motivated PhD students.

Contact: iino_at_ims.ac.jp (change _at_ to @)

News from our group, Old news

[Recent Publications]

Oct 17, 2019 Jun's paper has been published in ACS Photonics!
Multicolor high-speed tracking of single biomolecules with silver, gold, silver-gold alloy nanoparticles

Sep 13, 2019 Tatsuya's paper has been published in J. Biol. Chem. !
Single-molecule analysis reveals rotational substeps and chemo-mechanical coupling scheme of Enterococcus hirae V1-ATPase
Press release in EurekAlert

Aug 22, 2019 Yi's paper has been published in Science Advances!
Accurate high-throughput screening based on digital protein synthesis in a massively parallel femtoliter droplet array

Mar 16, 2019 Takayuki and Shingo's paper has been published in BBA Gereral Subjects!.
High-speed near-field fluorescence microscopy combined with high-speed atomic force microscopy for biological studies

[Awards and Transfers]

Nov 25, 2019 We had a farewell party for Jun! He will move to RIKEN as a tenured Research Scientist from Dec. 1st. Congratulations!

Oct 25, 2019 We had a farewell party for Yamamoto-san, an outstanding technical assistant. Thank you for tremendous contribution to the lab for 4.5 years!

Sep 25-26, 2019 Aki got Early Research Award and Tatsuya got Student Presentation Award of the Biophysical Society of Japan! Congratulations!

[Presentations and Events]

Feb 24, 2020 Iino give talk in Oregon State University

Feb 24, 2020 Iino give talk in 2020 Biophysical society annual meeting @San Diego

Jan 8, 2020 The 1st International Symposium on Molecular Engine @Chiba

Nov 19, 2019 Aki give a talk in APPC2019 @Kuching, Sarawak, Malaysia Program

Oct 28-30, 2019 Iino give a talk at NIBB-Princeton Joint Symposium @Okazaki

Oct 2-10, 2019 Iino visit Univ of Bristol, Univ of Edinburg, Univ of Manchester, Univ of Southampton in UK

Sep 30, 2019 Iino give atalk in Tokyo ATPase Workshop @U. Tokyo, Tokyo

Sep 24-26, 2019 Lab members and collaborators give 11 presentations in 57th Annual Meeting of the Biophysical Society of Japan.

Sep 4-6, 2019 Iino give a talk at Toyota RIKEN international workshop @Nagakute

Aug 7, 2019 Iino give a talk at Academia Sinica @Taipei Canceled due to gout attack. Sorry

July 29-31, 2019 Iino give a talk at Japan-Korea Molecular Science Symposium @Nagoya

July 25-27, 2019 Iino give a talk at 2nd East Asian Symposium on Single-Molecule Biological Sciences @Seoul

Jun 3-7, 2019 Iino visit Prof. Haw Yang lab @ Princeton University, NJ, USA

May 30, 2019 Iino give a talk at Joint Meeting for Young Researchers "Frontiers in Imaging Probes and Technologies" @Okazaki

Mar 13, 2019 Iino give a talk at 24th Flagella Meeting @Gamagori, Japan

Mar 2-6, 2019 Iino give a presentation at Biophysical Society 63rd Annual Meeting @Baltimore, USA

Feb 11, 2019 Iino give a talk at NCCR Molecular Systems Engineering, University of Basel, Switzerland

Jan 21-24, 2019 Iino visit Princeton University, NJ, USA

Jan 15, 2019 Iino give a talk at LaSIE Seminar, Osaka University, Osaka, Japan